منابع مشابه
A pre-structured helix in the intrinsically disordered 4EBP1.
The eIF4E-binding protein 1 (4EBP1) has long been known to be completely unstructured without any secondary structures, which contributed significantly to the proposal of the induced fit mechanism for target binding of intrinsically disordered proteins. We show here that 4EBP1 is not completely unstructured, but contains a pre-structured helix.
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2017
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-17-0042